Each of your responses should be one or more paragraphs long, depending upon the depth of the question. (An answer consisting of only a few short sentences is insufficient, and will receive a poor grade.)

  1. Discuss the human Y chromosome. Compare the human X and Y chromosomes in terms of size and number of genes. Describe in detail how the Y chromosome determines maleness in humans.
  2. Why are calico cats almost always female? In what rare circumstances is a male calico cat possible? Explain the details of the cellular mechanisms that result in their patchwork coat color. In your explanation, be sure to define the following terms: X-inactivation, dosage compensation, Barr body and the Lyon hypothesis.

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