1.GAPs (GTPase activating proteins) act on G proteins to…

A.

stimulate GTP hydrolysis, thereby turning the G protein “on.”

B.

stimulate GTP binding, thereby turning the G protein “off.”

C.

stimulate GTP hydrolysis, thereby turning the G protein “off.”

D.

stimulate GTP binding, thereby turning the G protein “on.”

QUESTION 2

1.Transautophosphorylation occurs on

A.

guanylyl cyclases

B.

receptor tyrosine kinases

C.

transmembrane scaffolds

D.

G protein-coupled receptors

QUESTION 3

1.Local mediators are ligands that are involved in

A.

paracrine signaling

B.

synaptic signaling

C.

contact-dependent signaling

D.

endocrine signaling

QUESTION 4

1.Which of these are NOT signal termination mechanisms?

A.

Release of ligand from its receptor

B.

G protein reformation (Gα + Gβγ = Gαβγ)

C.

G protein hydrolysis of GTP (G-GDP)

D.

Second messenger release

QUESTION 5

1.A lipid-soluble ligand would be expected to bind to a

A.

Second messenger

B.

transmembrane receptor

C.

G protein coupled receptor

D.

nuclear receptor

QUESTION 6

1.Which amino acid is NOT mainly phosphorylated by a protein kinase?

A.

threonine

B.

serine

C.

tyrosine

D.

lysine

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